HGH Dimer and Related Protein Content
I’m currently looking to begin a HGH protocol, so I started to review available testing from sources on the board.
A question that I haven’t been able to determine when browsing through the forum is related to HGH and dimer content. I understand that dimer’s are bound proteins that act differently than monomer’s (therefore reducing the efficacy of the product tested), however, I’m having a hard time finding a “cut-off” for what acceptable dimer content is. In May 2018, @Janoshik replied to a post noting that anything below 4% falls within pharma grade, however, can you folks share what you would consider unacceptable dimer content (e.g. anything > 1.2% you would not purchase.)
Additionally, are there any known side-effects related to dimer content? Since it’s generic GH, I realize that we can only discuss anecdotally reported adverse events, but I wanted to hear thoughts here as well.
Thank you all, look forward to learning from those of you who have spent time with the compound.
Anecdotally, I’d like to see 0.1% at most - most prominently, there’s a discussion on ‘goldtropin’ or so in Meso’s HGH section that are 99.5% purity with 0.5% dimer iirc and crippling people with side effects left and right, so especially for those wanting to take >3iu daily, minimizing dimer & thus side effects should be a priority.
@TheHumbleConquistador Hey I couldn’t find the thread where you were asking what the dimer actually is and you were asking for microbiologists.
I am a biologist and currently applying to medical school I would like to give my thoughts on this since I couldn’t find anything either. I could be 100% wrong though.
So you are right, a dimer is two monomer proteins bound together. I imagine this happens through the lyophilization process, which is just a fancy term for freeze drying. I would imagine that if two of the monomers were bound together, thereby forming a dimer, it would just be rendered inactive. So I would venture to guess that you could just consider dimer content inactive growth.
@Liska Thank you for your perspective! And I actually do remember that specific thread on Meso. If I recall, the conversation ran for some time with everyone positing different sides.
@JAKRPH Appreciate your thoughts as well! That explanation makes sense and is a straightforward way to think of it (and it logically makes sense as well). Thanks for jumping in and giving that view, I always thought it would be interesting to go to school for that (I don’t think I could have made it through), so good luck with your studies!